Topical treatments and lesion-directed treatments

This course, presented by Dr. Zoe Apalla, offers a focused exploration of treatments for actinic keratosis and lesion-directed approaches in skin cancer medicine.

This course provides a complete guide to managing actinic keratosis using various therapeutic techniques, including lesion- and field-directed treatments. Key topics include:
- Introduction to Actinic Keratosis: Learn about the pathogenesis, clinical presentation, and classification of actinic keratosis, as well as the risks of progression to squamous cell carcinoma. Dermoscopic patterns and clinical examples enhance diagnostic accuracy.
- Lesion-Directed Treatments:
- Cryotherapy: Explore the science behind liquid nitrogen application, including techniques, delivery methods, and optimal freeze times. Understand its effectiveness for various lesion types and tips for minimising adverse effects.
- Curettage with Electrodessication: Discover the technique for removing hypertrophic lesions, its benefits, and its role in providing tissue for histological examination.
- Topical 5-Fluorouracil (5-FU): Study its dual role as a lesion- and field-directed treatment, suitable concentrations, and associated clearance rates. Case studies illustrate treatment outcomes and management of side effects.
- Advanced Therapies:
- Surgical Excision: Understand its selective use for resistant or diagnostically ambiguous lesions.
- Laser Treatments: Review the use of ablative lasers like carbon dioxide and erbium lasers for lesion destruction, their effectiveness, and associated risks.
- Combination Therapies: Explore synergistic approaches such as combining cryotherapy with topical agents or laser resurfacing, optimising therapeutic and cosmetic outcomes.

This course incorporates clinical images, systematic reviews, and practical advice, ensuring a thorough understanding of treatment modalities. Ideal for general practitioners and specialists, this module delivers actionable skills for improved patient care in skin cancer medicine.

1. Summarise key features and elements of topical skin cancer treatments as an overview of this field.
2. Recommend key features and elements of lesion directed treatments and how to apply them safely, including liquid nitrogen and 5-FU in salicylic acid.
   
   

All degree qualified medical practitioners.